Publisher's Weekly Review

"No one system, organ, or other factor is responsible for depression not one steroid, not one gene, not one neurotransmitter, and not a lesion on one side of the brain or the other. What we seem to have is... a stew with lots of different and exotic ingredients." So explains DePaulo (How to Cope with Depression), psychiatry professor and director of the Affective Mental Disorders Clinic at the Johns Hopkins School of Medicine, in this thoughtful, exhaustive reference on depression for general readers. DePaulo covers all aspects of the illness what it feels like; who tends to have it (women are two or three times more likely to be diagnosed than men, not necessarily the same thing); the biology of depression; possible courses of therapy; and psychopharmacology. DePaulo also discusses bipolar disorder (manic depression), and he covers both mainstream and alternative treatments. He believes doctors should involve family and friends of the patient (which, though ideal, is probably impractical for doctors on most health-care plans), and explains how the children and other family members of those with depression are affected by the disease. The chapters on finding the right treatment and how doctors make diagnoses will be extremely useful for those suffering from the disease. Though some of the writing is a touch sloppy and clunky, readers will find this an invaluable resource. (Mar.) FYI: Dana Press is the publishing arm of the Dana Foundation, a 40-year-old organization that supports brain research. (c) Copyright PWxyz, LLC. All rights reserved